I recently gave a lightning talk on "The Cure for Cancer".
Here was the original concept outline:
1) History of medicine
'While I will tell you the cure for cancer today, I want you to think more deeply about what a cure really is. In reality we're raising issues about how we think about medicine. here's an old-timey chirgeon ... this is what medicine used to be. In the modern era ...
2) Cure for cancer
Cancer = cells that replicate without end.
The body has one good mechanism that stops this. [slide of car's kill switch] It is one of the most defining features of cellular anatomy. Your body ALWAYS retains the right to stop replication.
[slide explaining difference between malignant and benign ... telomeres] Life-threatening cancers are cancers because they turn on ONE specific gene. There are all sorts of malignant genes you could turn on -- but cancer is defined by finding this gene, and running amok.
3) Biology vs Engineering
Biologically we treat cancer by learning about the body's natural defenses, and reinforcing these, or by learning about cancer's natural weaknesses, and reinforcing these.
Engineering-wise, it has been suggested that having a detonator switch in the body is a bad idea and we should take it out entirely. Yes, you would die within 10 years, BUT you could AGAIN re-engineer ... by re-seeding cells with longer telomeres every 9 years.
4) Bottomline:
[slide showing different kinds of 'engineering' solutions for different untreatable conditions]
This theoretical but definitive cure for cancer raises all kinds of uncomfortable issues and creates dependence on a centralized establishment for continuing life.
But the scope of problem changes from theoretical understanding to active manipulation.
[slide of chirgeon => surgeon => bladerunner surgeon]
The paradigm will shift during your lifetime.